Vyvanse vs Adderall: Which Is the Ultimate Study Enhancer

Vyvanse vs Adderall Which is the Ultimate Study Enhancer

Before we get to the heart of the argument another issue need to be brought up. Is it really safe to even take Adderall and Vyvanse just to stimulate the brain to study? These are drugs usually used to control ADHD not to routinely boost a study session. What if some naturally brilliant student starts taking either one of these chemical enhancers and becomes addicted. How do scientists and researchers even know if these drugs don’t cause long term brain damage down the road? Anyway, let’s get to the point of this article as to which of these drugs is better for studying.

What is Vyvanse?

We will take at that powerhouse called vyvanse first and by the way it’s official name is Lisdexamfetamine but tell me, who in the world is going to say that mouth full every time when you can simply say vyvanse? Vyvanse is a prodrug (a biologically inactive compound that can be metabolized in the body to produce a drug.) of the central nervous system stimulant dextroamphetamine, a phenethylamine of the amphetamine class, which is used to treat ADHD and binge eating disorder. Theses conditions seem to p;oar opposite bt this drug is able to help both conditions. Apparently, this drug was not even designed to be consumed for enhanced studying but two extremely different conditions. To be able to treat these conditions this has to be a very powerful drug indeed. The drug’s chemical structure consists of dextroamphetamine and the amino acid L-lysine. The actual drug itself is inactive prior to absorption into the body. Then when it is absorbed the rate limit of the enzymatic cleavage of the L-lysine portion, which manufactures the active metabolite (dextroamphetamine). In simple terms once the drug is absorbed into your system the L-lysine portion will activate the dextroamphetamine component in a controlled and limited quantity. This drug is so powerful it released in limited portions. Vyvanse is diagnosed for children 6 years and older who have ADHD and for adults only with binge eating disorder. Never give this medication to children 3 to 5 years old who have ADHD. The effects of this drug on the little ones have not been determined.         

This is concerning this drug is listed as a Class B/Schedule II substance in the United Kingdom and a Schedule II controlled substance in the United States. (DEA number 1205) and in 2016 the quota for manufacture of this drug was listed at 29,750 kilograms of anhydrous acid or base. Considering this drug is a controlled substance, has a DEA number, and is limited in production numbers indicates it is a drug that can be dangerous and easily addictive. How can a drug with these types of controls be legal or even beneficial for people who are taking for it study purposes only.

Studies indicate high doses of vyvanse given to animals causes a dopamine effect and or nerve damage. It is reported people who take it for ADHD have improved brain development and nerve growth. These people have ADHD and they are not taking it for studying purposes. Furthermore, studies have shown that people with ADHD who have taken this drug they have had brain abnormalities and behavioral issues corrected. This after long term use of this drug. Studies have concluded that the effectiveness and safety of the drug is valid these trials have been carried on for two years. This is quite different than using the drug for study purposes.

Other reviews have stated the drug has been effective in treating academics, antisocial behavior, driving, non-medicinal drug use, obesity, occupation, self-esteem, service use (i.e., academic, occupational, health, financial, and legal services), and social function which are key factors of ADHD. Notice the word study was used in relation to people with ADHD not people without this brain condition. Another nine month study concluded that children with ADHD who took this drug showed improvement in an average increase of 4.5 IQ points, continued increases in attention, and continued decreases in disruptive behaviors and hyperactivity. One long term study predicted children who took the drug would for a lifetime would show reduces symptoms of ADHD and have no substance abuse disorders.

 

Physical Side Effects      

The physical side effects of this drug will vary from person to person and age of course will factor into these side effects. The effects range from cardiovascular which produces hypertension from a vasovagal response, to Raynaud’s phenomenon (reduced blood flow to the hands and feet), and tachycardia (increased heart rate). Other effects include erectile dysfunction in males, frequent erections, and prolonged erections. These don’t sound like healthy side effects. Abdominal side effects include nausea, abdominal pain, appetite loss, and weight loss. Other effects could be blurred vision, dry mouth, excessive grinding of the teeth, nosebleed, profuse sweating, rhinitis medicamentosa (drug-induced nasal congestion), reduced seizure threshold, and tics (a type of movement disorder).] Dangerous physical side effects are rare at typical pharmaceutical doses.

But they do exist. It seems plausible this drug is not a good alternative to use as a study enhancer.

 

Oh Boy Psychological

You mean to tell me there is mental effects as well? Yes, there are the the most common ones include increased alertness, apprehension, concentration, initiative, self-confidence, and sociability, mood swings (elated mood followed by mildly depressed mood), insomnia or wakefulness, and decreased sense of fatigue. The less common effects are Less common side effects include anxiety, change in libido, grandiosity, irritability, repetitive or obsessive behaviors, and restlessness;[these effects depend on the user’s personality and current mental state. That is a great comfort!

 

Overdose Effects

Typically amphetamine poisoning results in convulsions and coma

If these were not enough there are effects from abuse. It is rarely fatal if taken care of properly. The effects increased with dosage but decrease with tolerance to amphetamines. Some people take 5 grams of amphetamine a day which is 100 times the normal dose and they have no effects. Typically amphetamine poisoning results in convulsions and coma.  In 2013 there were

An estimated 3,788 deaths reported from Vyvanse overdose.

 

Minor or Moderate Overdose Effects

 

Cardiovascular

  • Abnormal heartbeat
  • High or low blood pressure

 

Central Nervous System

  • Confusion
  • Abnormally fast reflexes
  • Severe agitation
  • Tremor (involuntary muscle twitching)

 

Musculoskeletal

Muscle pain

 

Respiratory

Rapid breathing

 

Urinary

  • Painful urination
  • Urinary retention (inability to urinate)

 

Other

  • Elevated body temperature
  • Mydriasis (dilated pupils)

 

Severe Overdose Effects

Severe Overdose Effects

 

Cardiovascular

  • Cardiogenic shock (heart not pumping enough blood)
  • Cerebral hemorrhage (bleeding in the brain) This is very serious
  • Circulatory collapse (partial or complete failure of the circulatory system)

 

Central Nervous System

  • Acute amphetamine psychosis (e.g., delusions and paranoia)
  • Compulsive and repetitive movement
  • Serotonin syndrome (excessive serotonergic nerve activity)
  • Sympathomimetic toxidrome (excessive adrenergic nerve activity)

 

Musculoskeletal

Rhabdomyolysis (rapid muscle breakdown)

 

Respiratory

  • Pulmonary edema (fluid accumulation in the lungs)
  • Pulmonary hypertension (high blood pressure in the arteries of the lung)
  • Respiratory alkalosis (reduced blood CO2)

 

Urinary

  • No urine production
  • Kidney failure

 

Other

  • Elevated or low blood potassium
  • Hyperpyrexia (extremely elevated core body temperature)
  • Metabolic acidosis (excessively acidic bodily fluids)

 

What is Adderall?

Adderall is made of two salts of the two enantiomers of amphetamine which is a central nervous system stimulant of the phenethylamine class. This particular drug treats ADHD and narcolepsy (tendency to fall asleep whenever in relaxed surroundings) it is uses as an athletic performance enhancer, cognitive enhancer, and recreationally as an aphrodisiac and euphoriant. Compared to Vyvanse the uses are a little different. Adderall is generally effective in treating  ADHD but at therapeutic doses it causes emotional and cognitive effects such as euphoria, change in desire for sex, increased wakefulness, and improved cognitive control. In these doses it causes physical effects as decreased reaction time, fatigue resistance, and increased muscle strength. Conversely, larger doses of adderall will cause much larger doses of Adderall can impair cognitive control, cause rapid muscle breakdown, or induce a psychosis (e.g., delusions and paranoia). With this drug (as with Vyvanse) the side effects of adderall vary widely with individuals.

The more common side effects are insomnia, dry mouth, and loss of appetite. Used in low doses for ADHD adderall is usually non-addictive but unfortunately when it is taken at higher doses addiction becomes very likely. This is due to the reinforcing agents that are present; adderall taken for recreational uses can have adverse side effects. This is why is it safe to use this drug as a study enhancer?  The two salt enantiomers are the keys to treating ADHD and alleviate the symptoms of this condition.

Adderall’s active ingredient, amphetamine, shares many of the chemical and pharmacological properties with the human trace amines, particularly phenethylamine and N-methylphenethylamine, the latter of which is a positional isomer of amphetamine. Which means this drug interacts deeply with the body to treat ADHD.  

 

Physical Side Effects       

Before the physical side effects are discussed adderall will have different side effects from person to person. The amount of adderall taken will determine the severity of the side effects. It is approved for long term therapeutic uses by the USFDA but recreational uses are consumed at much higher levels and these quantities will cause serious adverse effects as was mentioned before.

Physical effects involve hypertension, from a vasovagal response, Raynaud’s phenomenon (reduced blood flow to the hands and feet), and tachycardia (increased heart rate). Sexual side effects in males may include erectile dysfunction, frequent erections, or prolonged erections. Abdominal side effects may include abdominal pain, appetite loss, nausea, and weight loss. These side effects are identical to some of the side effects of Vyvanse. Adderall stimulates medullary respiratory centers, producing faster and deeper breaths. In normal doses this effect will not be noticeable but if the condition already exists it will be seen. It also induces contraction in the urinary bladder sphincter, the muscle which controls urination, which can result in difficulty urinating. These are side effects but they can help with bed wetting and loss of bladder control. The side effects of adderall on the gastrointestinal system is unpredictable.      

 

Psychological Side Effects

The side effects from normal therapeutic use include increased alertness

The side effects from normal therapeutic use include increased alertness, apprehension, concentration, initiative, self-confidence, and sociability, mood swings (elated mood followed by mildly depressed mood), insomnia or wakefulness, and decreased sense of fatigue. Less common side effects are anxiety change in libido, grandiosity, irritability, repetitive or obsessive behaviors, and restlessness;] these effects depend on the user’s personality and current mental state. Heavier users will experience Amphetamine psychosis (e.g., delusions and paranoia) can occur in heavy users  Although very rare, this psychosis can also occur at therapeutic doses during long-term therapy.

 

Lesser Overdose  Effects

 

Cardiovascular

  • Abnormal heartbeat
  • High or low blood pressure

 

Central Nervous System

  • Confusion
  • Abnormally fast reflexes
  • Severe agitation
  • Tremor (involuntary muscle twitching)

 

Musculoskeletal

  • Muscle pain

 

Respiratory

  • Rapid breathing

 

Urinary

  • Painful urination
  • Urinary retention (inability to urinate)

 

Other

  • Elevated body temperature
  • Mydriasis (dilated pupils)

 

Severe Overdose Side Effects

Actual Case of Adderall vs Vyvanse

 

Cardiovascular

  • Cardiogenic shock (heart not pumping enough blood)
  • Cerebral hemorrhage (bleeding in the brain)
  • Circulatory collapse (partial or complete failure of the circulatory system)

 

Central Nervous System

  • Acute amphetamine psychosis (e.g., delusions and paranoia)
  • Compulsive and repetitive movement
  • Serotonin syndrome (excessive serotonergic nerve activity)
  • Sympathomimetic toxidrome (excessive adrenergic nerve activity)

 

Musculoskeletal

Rhabdomyolysis (rapid muscle breakdown)

 

Respiratory

  • Pulmonary edema (fluid accumulation in the lungs)
  • Pulmonary hypertension (high blood pressure in the arteries of the lung)
  • Respiratory alkalosis (reduced blood CO2)

 

Urinary

  • No urine production
  • Kidney failure

 

Other

  • Elevated or low blood potassium
  • Hyperpyrexia (extremely elevated core body temperature)
  • Metabolic acidosis (excessively acidic bodily fluids)

 

Actual Case of Adderall vs Vyvanse

Adderall has been around longer than Vyvanse. Adderall came on the scene in 1996 with Vyvanse came into existence in 2007. Both treat ADHD effectively and work about in the same ways. Both are a stimulant medication and both are amphetamines. They stimulate the nervous system and increase the amount of neurotransmitters such as dopamine and norepinephrine in the brain. Both drugs are approved to help children six years old and above, who have ADHD, for classroom studying. The negatives to both drugs are that if they are used for a long time that can become highly addictive.

Vyvanse is less likely to be abused like adderall would be. This because the body needs to breakdown the Vyvanse before it begins to work in the system. Another major concern for the potential misuse of amphetamines is because they give the body the feeling of euphoria or people get high off them. This makes them highly conducive to be abused. Another benefit of Vyvanse is that unlike other stimulants it cannot be inhaled or injected.This leaves adderall more likely to be abused because it can be inhaled and injected. The way the drugs are taken and the way they are released in the body can lead to very significant differences. Adderall comes in two various forms:

Immediate-release tablet: You can take this form two or three times per day. The effects of each tablet last three to four hours. Obviously people looking for fast-acting relief would choose this form.

Extended-release capsule (Adderall XR): You take this form only once per day, and the effects last 10 to 12 hours. This is for those who desire a longer term effect. The capsule is filled with beads. Half of the beads work right away, and the other half start to work later. In this way, the extended-release capsule provides two doses in one pill.

Vyvanse comes in a delayed-release capsule you take in the morning. The drug is inactive as was mentioned before) as it enters the body. Once the drug is in the body then the body slowly breaks it down into its active form. Once this occurs then the drug begins to work within the body. The effects can last up to 14 hours which is longer than adderall effects the body. Unfortunately there is no clear cut winner as to which drug works better as a study enhancer for those who have ADHD. They both work well to treat ADHD so it it really hard to tell which one would be the best drug to take for study enhancement. There have been very few head-to-head studies between the two drugs. So, again there is not a lot of clinical research available to say one is better than the other.   

Both drugs come in brand name forms and are about the same price. Adderall is available as a generic drug Vyvanse is not. Universally, generic brand of drugs will also be cheaper than brand name forms.

 

Final Thoughts     

Adderall is made of two salts of the two enantiomers of amphetamine

In analysis both drugs are effective for helping those with ADHD to study better. Both can have serious side effects if abused recreationally. In some cases the drugs can be fatal if abused over the long term. It is very hard to determine which drug has the edge when it comes to helping people with ADHD to improve their study skills. It must be noted that to take either drug just to improve study habits for those who don’t have ADHD is a bad choice. The drugs are both addictive with adderall being much more addictive than Vyvanse. In some cases the drugs have been fatal when abused. As reported earlier vyvanse caused 3788 deaths in 2013. This drug has the potential to kill  and adderall may be fatal as well if take in large quantities.  

Leave a Reply

Your email address will not be published. Required fields are marked *