Zembrin is marketed as mood enhancing herbal supplement that combats stress, reduces anxiety and eases tension. It’s also reported to sharpen focus, increase clarity, boost motivation and improve concentration.
Those are impressive claims, and a supplement that can deliver all of those benefits sounds like the perfect antidote to the stresses and complications of 21st century life.
In this Zembrin review I’m going to dig into those claims and attempt to give you the full picture surrounding Zembrin so that you can make an informed choice when deciding if this is the right supplement for your needs.
What Is Zembrin?
Zembrin is a botanical supplement that has been studied for safety and effectiveness in both clinical and preclinical trials and has a long history of use with the San and Khoikhoi peoples of South Africa who use the source of Zembrin – Sceletium tortuosum – to boost mood and ease fatigue, stress, and anxiety.
Zembrin is a patented, standardized extract of the South African Namaqualand plant, Sceletium tortuosum. Sceletium tortuosum is a succulent plant that grows in arid regions.
This herb known by San Bushmen as “kanna,” and “channa,” and by Dutch settlers as “kougoed,” has been used by the San people of South Africa for its mood altering properties since prehistoric times. Sceletium tortuosum was used and traded by San hunter-gatherers and pastoralists for medicinal, social and spiritual purposes. Colonial Dutch settlers also made use of the plant’s benefits.
While Sceletium tortuosum is known as a psychoactive herb, it isn’t known to be a hallucinogenic and is traditionally used to increase endurance, elevate mood, impart clarity of thinking, enhance decision making and reduce the effects of hunger, thirst and stress. Kanna is taken prior to stressful events such as hunting for its mind focusing effects and endurance enhancing effects.
While kanna is not a thirst-suppressant or hunger-suppressant, it is considered invaluable to help deal with the stress that arises from being thirsty or hungry when walking long distances in the wilderness.
Image copyright Dr Nigel Gericke
Sceletium tortuosum is a flowering succulent herb whose traditional preparation involves crushing all parts of the plants – leaves, stems, flowers and sometimes roots – and fermenting this material for up to a week. The fermented material is then dried in the sun. An alternative method omits the fermentation step. To gain the benefits of the herb, the dried material is chewed and the plants indigenous name “Kanna” means something to chew. Alternatively, the plant can be picked and dried without the fermentation step. The Sceletium tortuosum extract used in supplements is produced in a similar way, with the aerial parts of the plant being used.
Today, through a formal benefit-sharing agreement with the South African San Council, the developers of Zembrin, HG&H Pharmaceuticals, protect the interests of the San people who originally discovered this plant’s benefits. Because of this, Zembrin is the only Sceletium product to carry the logo of the South African San Council.
The Sceletium plant grows in the wild in South Africa, but is now a protected endangered species, so all of the plant materials used to produce Zembrin are cultivated on a commercial scale by the manufacturer. The controlled growing environment of this Sceletium tortuosum also allows the consistency of the source materials to be maintained.
With over ten years of research and development Zembrin is the only Sceletium extract to have the benefit of scientifically backed evidence for its claimed effects.
Lower doses of the Sceletium tortuosum extract are available without prescription, but the developers are hoping to produce a higher dose product as a botanical medicine for clinical use in the treatment of mental health diseases.
Pharmaceutical companies have shown considerable interest in this plant extract, and research grants have been provided by global leaders including Astrazeneca, Eli-Lilly, GlaxoSmithKline, Johnson & Johnson, Pfizer, Roche, and Wyeth.
The United States Federal Drug Administration (FDA) has recently approved the first-ever orally ingested botanical medicine, so the precedent has been set for exciting new treatments using ancient medicinal plant extracts like Zembrin in the future.
After an independent review of the preclinical and clinical studies by a panel of leading experts in the USA, Zembrin was formally designated as Generally Regarded As Safe (GRAS), in January 2011.
The safety and quality of Zembrin is assured, and it is manufactured to meet the highest international standards, being produced at a certified EU-GMP (European Union Good Manufacturing Practice) facility.
Zembrin is a 2:1 concentration of Sceletium based on dry weight and is equivalent to 16-50mg of the dry weight of the plant itself.
- has been given Generally Recognized As Safe (GRAS) status in USA.
- has been clinically studied for efficacy.
- has been studied for safety in pre-clinical and clinical studies.
- is the only Sceletium extract with published pharmacology.
- is manufactured at a certified EU-GMP manufacturer.
- is the first standardized extract to be made from Sceletium.
- is produced from a sustainable cultivated chemotype of Sceletium.
- is the only Sceletium product to carry the logo of the South African San Council.
Zembrin Benefits And Supporting Scientific Research
Continue reading “The Complete Guide to Zembrin”